Browsing Experimentally Confirmed database

Result: Your query found 43 resistance gene(s) from the BacMet Experimentally Confirmed database

Gene_nameExperimentally Verified Resistance Gene InformationPredicted Resistance Gene Information
acr3
  • BacMet ID: BAC0004
  • Code for: Efflux
  • Family: Acr3 family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Campylobacter jejuni
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: Arsenical-resistance membrane transporter; part of the an arsenic (ars) four-gene operon, containing genes encoding a putative membrane permease (ArsP), a transcriptional repressor (ArsR), an arsenate reductase (ArsC) and an arsenical-resistance membrane transporter (Acr3)
  • Length (amino acid): 347
  • Reference: Wang et al. 2009; Pubmed- 19502436

  • Similar resistance genes in 'BacMet Predicted database'
    aioA/aoxB
  • BacMet ID: BAC0020
  • Code for: Enzyme
  • Family: Prokaryotic molybdopterin-containing oxidoreductase family.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Herminiimonas arsenicoxydans
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: It is a structural gene which codes for small subunit of Arsenite oxidase aioAB; Involved in the detoxification of arsenic. Oxidizes As(III)O3- (arsenite) to the somewhat less toxic As(V)O4- (arsenate).
  • Length (amino acid): 826
  • Reference: Muller et al. 2003; Pubmed- 12486049, Cai et al. 2009; Pubmed- 19283378, Drewniak et al. 2013 Pubmed- 23454063,

  • Similar resistance genes in 'BacMet Predicted database'
    aioB/aoxA
  • BacMet ID: BAC0021
  • Code for: Enzyme
  • Family: Contains 1 Rieske domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Herminiimonas arsenicoxydans
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: It is a structural gene which codes for small subunit of Arsenite oxidase, AioAB; Involved in the detoxification of arsenic. Oxidizes As(III)O3- (arsenite) to the somewhat less toxic As(V)O4- (arsenate).
  • Length (amino acid): 173
  • Reference: Muller et al. 2003; Pubmed- 12486049, Cai et al. 2009; Pubmed- 19283378, Drewniak et al. 2013 Pubmed- 23454063

  • Similar resistance genes in 'BacMet Predicted database'
    aioR/aoxR
  • BacMet ID: BAC0022
  • Code for: Regulator
  • Family: Contains 1 sigma-54 factor interaction and 1 sigma-5factor interaction domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter)
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: Transcriptional regulator. Part of a two-component As(III) responsive system (AioSR)
  • Length (amino acid): 442
  • Reference: Kashyap et al. 2006; Pubmed- 16428412; Drewniak et al. 2013 Pubmed- 23454063, Muller et al. 2003; Pubmed- 12486049

  • Similar resistance genes in 'BacMet Predicted database'
    aioS/aoxS
  • BacMet ID: BAC0023
  • Code for: Regulator
  • Family: Contains histidine kinase domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter)
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: Sensor histidine kinase; signal transduction protein
  • Length (amino acid): 488
  • Reference: Kashyap et al. 2006; Pubmed- 16428412; Drewniak et al. 2013 Pubmed- 23454063, Muller et al. 2003; Pubmed- 12486049

  • Similar resistance genes in 'BacMet Predicted database'
    aioX/aoxX
  • BacMet ID: BAC0024
  • Code for: Binding protein
  • Family: ABC transporter superfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Rhizobium radiobacter (Agrobacterium tumefaciens) (Agrobacterium radiobacter)
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: A periplasmic oxyanion-binding protein involved in regulating arsenite oxidation
  • Length (amino acid): 306
  • Reference: Liu et al. 2012; Pubmed- 22176720, Cai et al. 2009; Pubmed- 19283378

  • Similar resistance genes in 'BacMet Predicted database'
    arsA
  • BacMet ID: BAC0030
  • Code for: Enzyme
  • Family: ArsA ATPase family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid IncN R46
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Anion-transporting ATPase; Determinants of a membrane-associated oxyanion-stimulated ATPase protein; energizes the arsenite efflux pump by ATP hydrolysis; Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents.
  • Length (amino acid): 583
  • Reference: Bruhn et al. 1996; Pubmed- 8674982

  • Similar resistance genes in 'BacMet Predicted database'
    arsA
  • BacMet ID: BAC0571
  • Code for: Enzyme
  • Family: ArsA ATPase family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acidiphilium multivorum (strain DSM 11245 / JCM 8867 / AIU301)
  • Location: Plasmid pKW301
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Anion-transporting ATPase. Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents.
  • Length (amino acid): 583
  • Reference: Suzuki et al. 1998; Pubmed- 9464374

  • Similar resistance genes in 'BacMet Predicted database'
    arsA
  • BacMet ID: BAC0572
  • Code for: Enzyme
  • Family: ArsA ATPase family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid R773
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Anion-transporting ATPase. Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents.
  • Length (amino acid): 583
  • Reference: Chen et al. 1986; Pubmed- 3021763

  • Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0031
  • Code for: Efflux
  • Family: ArsB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid R773 (E. coli), Plasmid IncN R46 (E. coli), Plasmid R46 (Salmonella typhimurium)
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Arsenic pump membrane protein, located in cell inner membrane. Involved in arsenite and antimonite resistance. Thought to form a channel of an arsenite pump.
  • Length (amino acid): 429
  • Reference: Tisa et al. 1990; Pubmed- 1688427, Chen et al. 1986; Pubmed- 3021763

  • Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0573
  • Code for: Regulator
  • Family: ACR3 family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Bacillus subtilis (strain 168)
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump. Deletion of the arsB gene results in both an aresenite- and arsenate-sensitive phenotype in the absence of IPTG.
  • Length (amino acid): 346
  • Reference: Sato et al. 1998; Pubmed- 9537360

  • Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0574
  • Code for: Efflux
  • Family: ArsB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Staphylococcus aureus
  • Location: Plasmid pI258
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
  • Length (amino acid): 429
  • Reference: Ji and Silver 1992; Pubmed- 1534328

  • Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0575
  • Code for: Efflux
  • Family: ArsB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Staphylococcus xylosus
  • Location: Plasmid pSX267
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
  • Length (amino acid): 429
  • Reference: Rosenstein et al. 1992; Pubmed- 1534327

  • Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0576
  • Code for: Efflux
  • Family: ArsB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid IncN R46
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
  • Length (amino acid): 429
  • Reference: Bruhn et al. 1996; Pubmed- 8674982

  • Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0577
  • Code for: Efflux
  • Family: ArsB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Yersinia enterocolitica
  • Location: Plasmid pYV
  • Compound: Arsenic (As)
  • Description: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
  • Length (amino acid): 429
  • Reference: Neyt et al. 1997; Pubmed- 9006011

  • Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0578
  • Code for: Efflux
  • Family: ArsB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acidiphilium multivorum (strain DSM 11245 / JCM 8867 / AIU301)
  • Location: Plasmid pKW301
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Part of arsenic resistance operon of Acidiphilium multivorum AIU 301 plasmid pKW301.
  • Length (amino acid): 429
  • Reference: Suzuki et al. 1998; Pubmed- 9464374

  • Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0579
  • Code for: Efflux
  • Family: ACR3 family.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Synechocystis sp. PCC 6803
  • Location: Chromosome
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Able to export both As(III) and Sb(III) and providies a example of convergent evolution between both families of arsenite transporters.
  • Length (amino acid): 383
  • Reference: Lopez-Maury et al. 2003; Pubmed- 12949088

  • Similar resistance genes in 'BacMet Predicted database'
    arsC
  • BacMet ID: BAC0032
  • Code for: Enzyme
  • Family: Low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Staphylococcus aureus
  • Location: Plasmid pI258
  • Compound: Arsenic (As)
  • Description: Arsenate reductase. Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances.
  • Length (amino acid): 131
  • Reference: Ji and Silver 1992; Pubmed- 1534328; Chen et al. 1986; Pubmed- 3021763

  • Similar resistance genes in 'BacMet Predicted database'
    arsC
  • BacMet ID: BAC0580
  • Code for: Enzyme
  • Family: Low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Staphylococcus xylosus
  • Location: Plasmid pSX267
  • Compound: Arsenic (As)
  • Description: Arsenate reductase. Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances.
  • Length (amino acid): 131
  • Reference: Rosenstein et al. 1992; Pubmed- 1534327

  • Similar resistance genes in 'BacMet Predicted database'
    arsC
  • BacMet ID: BAC0581
  • Code for: Enzyme
  • Family: Low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Bacillus subtilis (strain 168)
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: Arsenate reductase. Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances.
  • Length (amino acid): 139
  • Reference: Sato et al. 1998; Pubmed- 9537360

  • Similar resistance genes in 'BacMet Predicted database'
    arsC
  • BacMet ID: BAC0582
  • Code for: Enzyme
  • Family: arsC family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid R773
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance.
  • Length (amino acid): 141
  • Reference: Tisa et al. 1990; Pubmed- 1688427, Chen et al. 1986; Pubmed- 3021763

  • Similar resistance genes in 'BacMet Predicted database'
    arsC
  • BacMet ID: BAC0583
  • Code for: Enzyme
  • Family: arsC family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid IncN R46
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance.
  • Length (amino acid): 141
  • Reference: Bruhn et al. 1996; Pubmed- 8674982

  • Similar resistance genes in 'BacMet Predicted database'
    arsC
  • BacMet ID: BAC0584
  • Code for: Enzyme
  • Family: arsC family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acidiphilium multivorum (strain DSM 11245 / JCM 8867 / AIU301)
  • Location: Plasmid pKW301
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance
  • Length (amino acid): 141
  • Reference: Suzuki et al. 1998; Pubmed- 9464374

  • Similar resistance genes in 'BacMet Predicted database'
    arsC
  • BacMet ID: BAC0585
  • Code for: Enzyme
  • Family: arsC family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Yersinia enterocolitica
  • Location: Plasmid pYV
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance.
  • Length (amino acid): 141
  • Reference: Neyt et al. 1997; Pubmed- 9006011

  • Similar resistance genes in 'BacMet Predicted database'
    arsC
  • BacMet ID: BAC0586
  • Code for: Enzyme
  • Family: arsC family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Synechocystis sp. PCC 6803
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: Arsenate reductase. Reduces arsenate [As(V)] to arsenite [As(III)].
  • Length (amino acid): 131
  • Reference: Lopez-Maury et al. 2003; Pubmed- 12949088

  • Similar resistance genes in 'BacMet Predicted database'
    arsD
  • BacMet ID: BAC0033
  • Code for: Chaperone
  • Family: ArsD family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid R773 (E. coli), Plasmid R64 (Salmonella typhimurium)
  • Compound: Arsenic (As)
  • Description: An arsenic metallochaperone for an arsenic detoxification pump
  • Length (amino acid): 120
  • Reference: Wu et al. 1993; Pubmed- 8326869, Lin et al. 2006; Pubmed- 17030823

  • Similar resistance genes in 'BacMet Predicted database'
    arsD
  • BacMet ID: BAC0587
  • Code for: Regulator
  • Family: ArsD family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid IncN R46
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Arsenical resistance operon trans-acting repressor ArsD.
  • Length (amino acid): 120
  • Reference: Bruhn et al. 1996; Pubmed- 8674982

  • Similar resistance genes in 'BacMet Predicted database'
    arsH
  • BacMet ID: BAC0034
  • Code for: Enzyme
  • Family: NADPH-dependent FMN reductases family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Yersinia pestis Java 9
  • Location: Plasmid pKPN-IT (Klebsiella pneumoniae), Plasmid R485 (Morganella morganii (Proteus morganii))
  • Compound: Arsenic (As)
  • Description: Arsenical resistance protein ArsH; ArsH is not required for arsenate resistance in some systems; arsH encodes an NADPH-flavin mononucleotide oxidoreductase and has been shown to be involved in arsenic resistance in Yersinia enterocolitica and Sinorhizobium meliloti. It is an essential component in a new four gene arsenical resistance transposon associated operon, arsHRBC.
  • Length (amino acid): 232
  • Reference: Neyt et al. 1997; Pubmed- 9006011, Eppinger et al. 2012; Pubmed- 22479347

  • Similar resistance genes in 'BacMet Predicted database'
    arsM
  • BacMet ID: BAC0035
  • Code for: Enzyme
  • Family: Methyltransferase family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Rhodopseudomonas palustris CGA009
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: Arsenite S-adenosylmethyltransferase; involved in arsenite methyltransferase activity; arsM encodes an arsenite S-adenosylmethionine methyltransferase that methylates arsenite to volatile trimethylarsine, contributing to arsenic detoxification in bacteria.
  • Length (amino acid): 283
  • Reference: Qin et al. 2006; Pubmed- 16452170

  • Similar resistance genes in 'BacMet Predicted database'
    arsP
  • BacMet ID: BAC0036
  • Code for: Enzyme
  • Family: Major Facilitator Protein (MFP) Family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Campylobacter jejuni
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: arsenic resistance membrane permease
  • Length (amino acid): 315
  • Reference: Wang et al. 2009; Pubmed- 19502436

  • Similar resistance genes in 'BacMet Predicted database'
    arsR
  • BacMet ID: BAC0588
  • Code for: Regulator
  • Family: Contains 1 HTH arsR-type DNA-binding domain
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Yersinia enterocolitica
  • Location: Plasmid pYV
  • Compound: Arsenic (As)
  • Description: Arsenite inducible repressor ArsR
  • Length (amino acid): 117
  • Reference: Neyt et al. 1997; Pubmed- 9006011

  • Similar resistance genes in 'BacMet Predicted database'
    arsR
  • BacMet ID: BAC0589
  • Code for: Regulator
  • Family: Contains 1 HTH arsR-type DNA-binding domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid R773
  • Compound: Arsenic (As), Antimony (Sb), Bismuth (Bi)
  • Description: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)).
  • Length (amino acid): 117
  • Reference: Wu and Rosen 1991; Pubmed- 1838573

  • Similar resistance genes in 'BacMet Predicted database'
    arsR
  • BacMet ID: BAC0590
  • Code for: Regulator
  • Family: Contains 1 HTH arsR-type DNA-binding domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Staphylococcus aureus
  • Location: Plasmid pI258
  • Compound: Arsenic (As), Antimony (Sb), Bismuth (Bi)
  • Description: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)).
  • Length (amino acid): 104
  • Reference: Ji and Silver 1992; Pubmed- 1534328

  • Similar resistance genes in 'BacMet Predicted database'
    arsR
  • BacMet ID: BAC0591
  • Code for: Regulator
  • Family: Contains 1 HTH arsR-type DNA-binding domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid IncN R46
  • Compound: Arsenic (As), Antimony (Sb), Bismuth (Bi)
  • Description: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)).
  • Length (amino acid): 117
  • Reference: Bruhn et al. 1996; Pubmed- 8674982

  • Similar resistance genes in 'BacMet Predicted database'
    arsR
  • BacMet ID: BAC0592
  • Code for: Regulator
  • Family: Contains 1 HTH arsR-type DNA-binding domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Staphylococcus xylosus
  • Location: Plasmid pSX267
  • Compound: Arsenic (As), Antimony (Sb), Bismuth (Bi)
  • Description: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)).
  • Length (amino acid): 117
  • Reference: Rosenstein et al. 1992; Pubmed- 1534327

  • Similar resistance genes in 'BacMet Predicted database'
    arsR
  • BacMet ID: BAC0593
  • Code for: Regulator
  • Family: Contains 1 HTH arsR-type DNA-binding domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Bacillus subtilis (strain 168)
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: Transcriptional repressor for the ars operon.
  • Length (amino acid): 105
  • Reference: Sato et al. 1998; Pubmed- 9537360

  • Similar resistance genes in 'BacMet Predicted database'
    arsR
  • BacMet ID: BAC0594
  • Code for: Regulator
  • Family: Contains 1 HTH arsR-type DNA-binding domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: Transcriptional repressor for the arsEFG operon. ArsE is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)).
  • Length (amino acid): 117
  • Reference: Diorio et al. 1995; Pubmed- 7721697

  • Similar resistance genes in 'BacMet Predicted database'
    glpF
  • BacMet ID: BAC0181
  • Code for: Channel
  • Family: Major Intrinsic protein (MIP) superfamily. MIP/aquaporin family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Antimony (Sb), Arsenic (As), Glycerol [class: Alcohol]
  • Description: Glycerol uptake facilitator protein GlpF; Transporter of glycerol across the cytoplasmic membrane, with limited permeability to water and small uncharged compounds such as polyols
  • Length (amino acid): 281
  • Reference: Sanders et al. 1997; Pubmed- 9150238, Meng et al. 2004; Pubmed- 14970228

  • Similar resistance genes in 'BacMet Predicted database'
    pgpA/ltpgpA
  • BacMet ID: BAC0311
  • Code for: Enzyme
  • Family: ABC transporter superfamily. ABCB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Leishmania tarentolae (Sauroleishmania tarentolae)
  • Location: Chromosome
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Multidrug resistance protein PgpA
  • Length (amino acid): 1548
  • Reference: Papadopoulou et al. 1994; Pubmed- 7909316, Callahan et al. 1994; Pubmed- 7891738

  • Similar resistance genes in 'BacMet Predicted database'
    pstA
  • BacMet ID: BAC0315
  • Code for: Enzyme
  • Family: binding-protein-dependent transport system permease family. CysTW subfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: An integral membrane protein. Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
  • Length (amino acid): 296
  • Reference: Willsky et al. 1980; Pubmed- 6998959, Willsky et al. 1980; Pubmed- 6998957, Surin et al. 1985; Pubmed- 3881386

  • Similar resistance genes in 'BacMet Predicted database'
    pstB
  • BacMet ID: BAC0316
  • Code for: Enzyme
  • Family: ABC transporter superfamily. Phospahte importer family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: Phosphate transporting ATPase; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system.
  • Length (amino acid): 257
  • Reference: Willsky et al. 1980; Pubmed- 6998959, Willsky et al. 1980; Pubmed- 6998957, Surin et al. 1985; Pubmed- 3881386

  • Similar resistance genes in 'BacMet Predicted database'
    pstC
  • BacMet ID: BAC0317
  • Code for: Enzyme
  • Family: Binding-protein-dependent transport system permease family. CysTW subfamily
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: An integral membrane permease protein; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
  • Length (amino acid): 319
  • Reference: Willsky et al. 1980; Pubmed- 6998959, Willsky et al. 1980; Pubmed- 6998957, Surin et al. 1985; Pubmed- 3881386

  • Similar resistance genes in 'BacMet Predicted database'
    pstS
  • BacMet ID: BAC0318
  • Code for: Binding protein
  • Family: PstS family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Arsenic (As)
  • Description: A periplasmic phosphate binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import.
  • Length (amino acid): 346
  • Reference: Willsky et al. 1980; Pubmed- 6998959, Willsky et al. 1980; Pubmed- 6998957, Surin et al. 1984; Pubmed- 6321434

  • Similar resistance genes in 'BacMet Predicted database'

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